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Merck

S1068

Sigma-Aldrich

SB-215505

solid, >98% (HPLC)

别名:

6-Chloro-5-methyl-1-5-quinolycarbamoyl-indoline

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About This Item

经验公式(希尔记法):
C19H16N3OCl
分子量:
337.80
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

>98% (HPLC)

形狀

solid

顏色

off-white

溶解度

DMSO: soluble ~11 mg/mL at 60 °C
H2O: insoluble

起源

GlaxoSmithKline

儲存溫度

2-8°C

SMILES 字串

Cc1cc2CCN(C(=O)Nc3ccnc4ccccc34)c2cc1Cl

InChI

1S/C19H16ClN3O/c1-12-10-13-7-9-23(18(13)11-15(12)20)19(24)22-17-6-8-21-16-5-3-2-4-14(16)17/h2-6,8,10-11H,7,9H2,1H3,(H,21,22,24)

InChI 密鑰

BPVGSWDWIRIUME-UHFFFAOYSA-N

基因資訊

human ... HTR2B(3357)

生化/生理作用

Selective 5-HT2B serotonin receptor antagonist; 100-fold higher affinity at 2B versus 2C.

特點和優勢

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律資訊

Sold for research purposes under agreement from Glaxo­Smith­Kline

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Adam J Isabella et al.
Developmental cell, 53(3), 344-357 (2020-04-18)
Information flow through neural circuits often requires their organization into topographic maps in which the positions of cell bodies and synaptic targets correspond. To understand how topographic map development is controlled, we examine the mechanism underlying targeting of vagus motor

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