化驗
>98% (HPLC)
形狀
solid
顏色
off-white
溶解度
DMSO: soluble ~11 mg/mL at 60 °C
H2O: insoluble
起源
GlaxoSmithKline
儲存溫度
2-8°C
SMILES 字串
Cc1cc2CCN(C(=O)Nc3ccnc4ccccc34)c2cc1Cl
InChI
1S/C19H16ClN3O/c1-12-10-13-7-9-23(18(13)11-15(12)20)19(24)22-17-6-8-21-16-5-3-2-4-14(16)17/h2-6,8,10-11H,7,9H2,1H3,(H,21,22,24)
InChI 密鑰
BPVGSWDWIRIUME-UHFFFAOYSA-N
基因資訊
human ... HTR2B(3357)
生化/生理作用
Selective 5-HT2B serotonin receptor antagonist; 100-fold higher affinity at 2B versus 2C.
特點和優勢
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律資訊
Sold for research purposes under agreement from GlaxoSmithKline
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Developmental cell, 53(3), 344-357 (2020-04-18)
Information flow through neural circuits often requires their organization into topographic maps in which the positions of cell bodies and synaptic targets correspond. To understand how topographic map development is controlled, we examine the mechanism underlying targeting of vagus motor
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