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Merck
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Key Documents

RAB1652

Sigma-Aldrich

人PSP94 ELISA

for serum, plasma and cell culture supernatants

别名:

β-Microseminoprotein, Beta-microseminoprotein , IGBF, Immunoglobulin-binding factor, Prostate secretory protein of 94 amino acids

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

human

技術

ELISA: suitable

輸入

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... MSMB(4477)

一般說明

The prostate secretory protein of 94 amino acids (PSP94), which is secreted by the prostate gland, is a small, cysteine-rich, and non-glycosylated protein. It is found abundantly in prostatic secretions and is a primary constituent of human semen. Lower expression of the PSP94 gene is observed in prostate cancer. PSP94 acts as a tumor suppressor and curbs metastasis. It also acts as an inhibitor of sperm motility and sperm acrosome reaction. The PSP94 gene is located on the human chromosome at 10q11.22.

應用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

其他說明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Bhakti R Pathak et al.
Asian journal of andrology, 12(5), 677-689 (2010-08-03)
The prostate secretory protein of 94 amino acids (PSP94) has been shown to interact with cysteine-rich secretory protein 3 (CRISP-3) in human seminal plasma. Interestingly, PSP94 expression is reduced or lost in the majority of the prostate tumours, whereas CRISP-3
Ashwani Kumar et al.
Journal of molecular biology, 397(4), 947-956 (2010-02-27)
Several recent genome-wide association studies have linked the human MSMB gene, encoding prostate secretory protein of 94 residues (PSP94), with prostate cancer susceptibility. PSP94 is one of the most abundant proteins from prostatic secretions and a primary constituent of human
Zhaohui Du et al.
International journal of cancer, 146(7), 1819-1826 (2019-06-22)
Latinos represent <1% of samples analyzed to date in genome-wide association studies of cancer. The clinical value of genetic information in guiding personalized medicine in populations of non-European ancestry will require additional discovery and risk locus characterization efforts across populations.

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