RAB0659

Human FOLR1 / Folate Receptor Alpha ELISA Kit

• 分類程式碼代碼: 41116158
• NACRES: NA.84

属性

• 物種活性: human
• 包裝: kit of 96 wells (12 strips x 8 wells)
• 技術: ELISA: suitable
• 輸入: sample type cell culture supernatant(s); sample type plasma; sample type serum
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.1 ng/mL; standard curve range: 0.102-25 ng/mL
• 檢測方法: colorimetric
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... FOLR1(2348)

说明

一般說明

The antibody pair provided in this kit recognizes human Folate Receptor Alpha.
The folate receptor 1 (FOLR1) gene is mapped to human chromosome 11q13.4. The gene codes for a glycosylphosphatidylinositol protein that is attached to cell membranes. Folr1 is expressed in placenta, kidney tubules and choroid plexus.

應用

请参考Protocol了解详情。

生化／生理作用

Folate receptor 1 (FOLR1) plays a vital role in folate transport across the blood–brain barrier through the choroid plexus. It is also essential for neural tube closure during embryogenesis. Mutation in the gene leads to the development of cerebral folate deficiency in a few families. Overexpression of the gene has been observed in some epithelial malignancies including medulloblastoma, ovarian, lung and breast carcinomas. FOLR1 acts as a potential biomarker and therapeutic target for medulloblastoma.

试剂盒组分也可单独购买

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

安全信息

• 象形圖: GHS05
• 訊號詞: Warning
• 危險聲明: H290
• 防範說明: P234 - P390
• 危險分類: Met. Corr. 1
• 儲存類別代碼: 8B - Non-combustible corrosive hazardous materials
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable