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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 12 pg/mL
standard curve range: 16.38-4000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... FGF1(2246)
一般說明
FGF1 (fibroblast growth factor 1) gene encodes a member of the fibroblast growth factor (FGF) family. It encodes a pro-angiogenic protein that is ubiquitously expressed. In humans, FGF1 is alternatively spliced into four forms: FGF1A (in kidney), FGF1B (in brain), FGF1-C and -D (in vascular smooth muscle cells and fibroblasts). This gene is located on human chromosome 5q31.
應用
请参考Protocol了解详情。
生化／生理作用
FGF1 (fibroblast growth factor 1) is mainly involved in cell growth, proliferation and neurogenesis. It also participates in wound healing, post-ischemic heart repair and making of collaterals after hindlimb ischemia. FGF1 functions as an angiogenic factor that participates in tissue repair, carcinogenesis and maintenance of vasculature stability.
The FGF1 ELISA kit provides for the quantitative measurement of Fibroblast Growth Factor 1 in Cell Culture Supernatants, Plasma and Serum.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Upregulation of fibroblast growth factor 1 in the synovial membranes of patients with late stage osteoarthritis.
Li R, et al.
Genetics and molecular research : GMR, 14(3), 11191-11199 (2015)
Yash Chhabra et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6412-6430 (2019-02-20)
Growth hormone (GH) has an important function as an insulin antagonist with elevated insulin sensitivity evident in humans and mice lacking a functional GH receptor (GHR). We sought the molecular basis for this sensitivity by utilizing a panel of mice
Transgenic expression of nonclassically secreted FGF suppresses kidney repair.
Kirov A, et al.
PLoS ONE, 7(5), e36485-e36485 (2012)
Hongyu Guan et al.
Cell & bioscience, 8, 26-26 (2018-04-11)
Innate immunity activator (INAVA) has been shown to be elevated in lung adenocarcinoma. However, its expression pattern and function in papillary thyroid cancer (PTC) are unknown. This study aimed to identify the clinical, biological, and mechanistic impacts of INAVA on
Fibroblast growth factors.
Ornitz DM and Itoh N
Genome Biology, 2(3) (2001)
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