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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type serum
sample type urine
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 2.05-500 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... CSF2(1437)
一般說明
The Human GM-CSF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human GM-CSF in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human GM-CSF
應用
请参考Protocol了解详情。
生化／生理作用
GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It enhances neutrophil migration. GM-CSF plays a crucial role in inflammatory and autoimmune diseases. In neutrophils, it promotes the expression of TLR2 (toll-like receptor) and TLR2-associated interleukin 8 responses, thereby eliminating microbial attack.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8B - Non-combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD.
The European Respiratory Journal (2008)
GM-CSF in inflammation and autoimmunity.
Hamilton JA
Trends in Immunology (2002)
Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils.
Blood (2002)
Growth of clonogenic myeloblastic leukemic cells in the presence of human recombinant erythropoietin in addition to various human recombinant hematopoietic growth factors.
Asano Y
Blood (1988)
D Margriet Ouwens et al.
Diabetologia, 57(10), 2208-2214 (2014-07-19)
Type 1 diabetes is associated with moderate cognitive decline and cerebral alterations and may lead to an increased risk of dementia, including Alzheimer's disease. This study aimed to investigate the levels of risk markers for Alzheimer's disease in middle-aged patients
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