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Merck
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主要文件

PLA0119

Sigma-Aldrich

Rabbit anti-NONO Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

52 kDa subunit, 54 kDa nuclear RNA- and DNA-binding protein, 54-kD, 55 kDa nuclear protein, DNA-binding p52/p100 complex, MRXS34, NMT55, NRB54, NonO protein, Nuclear RNA-binding protein, P54, P54NRB, PPP1R114, non-Pou domain-containing octamer (ATGCAAAT) binding protein, p54(nrb), protein phosphatase 1, regulatory subunit 114

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

rat, mouse, human

技術

immunohistochemistry: 1:200-1:1,000
immunoprecipitation (IP): 1- 4 μg/mg
western blot: 1:2,000- 1:10,000

登錄號

NP_031389.3

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

rabbit ... NONO(4841)

免疫原

The epitope recognized by PLA0119 maps to a region between residues 350 and 400 of human Non-POU Domain Containing, Octamer-binding using the numbering given in entry NP_031389.3 (GeneID 4841).

外觀

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他說明

Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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