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Merck

P6636

Sigma-Aldrich

L-α-磷脂酰肌醇 来源于大豆

~50% (TLC)

别名:

1,2-二酰基-sn-甘油-3-磷酸基-(1-D-myo-肌醇), 阿法诺肽

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About This Item

CAS号:
Beilstein:
8535268
EC號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

生物源

soybean

形狀

crude powder

濃度

~50% (TLC)

官能基

phospholipid

脂質類型

phosphoglycerides

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C45H87O13P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(46)55-35-37(36-56-59(53,54)58-45-43(51)41(49)40(48)42(50)44(45)52)57-39(47)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37,40-45,48-52H,3-36H2,1-2H3,(H,53,54)/t37-,40?,41-,42+,43-,44-,45?/m1/s1

InChI 密鑰

FQZQXPXKJFOAGE-KAEDGTSCSA-N

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生化/生理作用

磷脂膜组分,磷酸肌醇的前体。

品質

可能含有磷脂酸和磷脂酰乙醇胺

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Tamar Burg-Golani et al.
Journal of bacteriology, 195(23), 5262-5272 (2013-09-24)
Listeria monocytogenes is a Gram-positive human intracellular pathogen that infects diverse mammalian cells. Upon invasion, L. monocytogenes secretes multiple virulence factors that target host cellular processes and promote infection. It has been presumed, but was not empirically established, that the
Qiangjun Zhou et al.
Nature communications, 5, 3552-3552 (2014-03-29)
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signalling and trafficking. Its kinase activity critically depends on palmitoylation of its cysteine-rich motif (-CCPCC-) and is modulated by the membrane environment. Lack of atomic structure
T Chakraborty et al.
Journal of bacteriology, 174(2), 568-574 (1992-01-01)
The prfA gene of Listeria monocytogenes encodes a protein that activates transcription of the listeriolysin gene (lisA). In order to explore the role of the prfA gene product in the pathogenesis of listerial infection, we constructed a site-directed insertion mutation
Lior Lobel et al.
Molecular microbiology, 95(4), 624-644 (2014-11-29)
Metabolic adaptations are critical to the ability of bacterial pathogens to grow within host cells and are normally preceded by sensing of host-specific metabolic signals, which in turn can influence the pathogen's virulence state. Previously, we reported that the intracellular
Adi Haber et al.
PLoS pathogens, 13(1), e1006161-e1006161 (2017-01-24)
The high environmental adaptability of bacteria is contingent upon their ability to sense changes in their surroundings. Bacterial pathogen entry into host poses an abrupt and dramatic environmental change, during which successful pathogens gauge multiple parameters that signal host localization.

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