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Merck

P4761

Sigma-Aldrich

聚 L -谷氨酸钠盐 钠盐

mol wt 15,000-50,000

别名:

L-Glutamic acid homopolymer sodium salt

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.25

形狀

powder

分子量

15,000-50,000

顏色

white to off-white

應用

detection

儲存溫度

−20°C

InChI

1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1

InChI 密鑰

BUZMZDDKFCSKOT-CIUDSAMLSA-N

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應用


  • Effect of Micelle-Incorporated Cisplatin With Sizes Ranging From 8 to 40 nm for the Therapy of Lewis Lung Carcinoma.: This research explores the use of micelle-incorporated cisplatin nanoparticles for cancer therapy, highlighting the significance of particle size on therapeutic efficacy. Poly-ʟ-glutamic acid sodium salt is used to improve drug delivery and target specificity (Wang Z et al., 2021).

  • Ternary Polypeptide Nanoparticles with Improved Encapsulation, Sustained Release, and Enhanced In Vitro Efficacy of Carfilzomib.: This paper describes the development of ternary polypeptide nanoparticles, including poly-ʟ-glutamic acid sodium salt, to enhance the encapsulation and release of carfilzomib, an anticancer drug. The study demonstrates improved drug efficacy and controlled release profiles (Agbana P et al., 2020).

  • Polymeric Core-Shell Nanoparticles Prepared by Spontaneous Emulsification Solvent Evaporation and Functionalized by the Layer-by-Layer Method.: This research focuses on the preparation of polymeric core-shell nanoparticles using a spontaneous emulsification method. Poly-ʟ-glutamic acid sodium salt is used to functionalize these nanoparticles, which can be applied in drug delivery systems (Szczęch M et al., 2020).

  • Co-administration of Combretastatin A4 Nanoparticles and Sorafenib for Systemic Therapy of Hepatocellular Carcinoma.: This study evaluates the combined use of combretastatin A4 nanoparticles and sorafenib for treating liver cancer. Poly-ʟ-glutamic acid sodium salt is employed to enhance the stability and delivery of these nanoparticles, showing promise in improving therapeutic outcomes (Wang Y et al., 2019).

分析報告

分子量基于粘度。

其他說明

有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Recently, the benefit of step-wise sequential delivery of fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 from a bioinspired apatite drug delivery system on mouse calvarial bone repair was demonstrated. The thicknesses of the nanostructured poly-l-Lysine/poly-l-Glutamic acid polyelectrolyte multilayer (PEM)

商品

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

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