化驗
≥96% (HPLC)
形狀
solid
顏色
yellow
溶解度
DMSO: >10 mg/mL
儲存溫度
−20°C
SMILES 字串
OCCSC1=C(SCCO)C(=O)N(C1=O)c2ccc(cc2)-c3ccccc3
InChI
1S/C20H19NO4S2/c22-10-12-26-17-18(27-13-11-23)20(25)21(19(17)24)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-9,22-23H,10-13H2
InChI 密鑰
RFZCIUONZTUZER-UHFFFAOYSA-N
生化/生理作用
PM-20 is a Cdc25A phosphatase inhibitor.
注意
air sensitive
Molecular cancer therapeutics, 5(6), 1511-1519 (2006-07-05)
We have synthesized several new phenyl maleimide compounds, which are potent growth inhibitors of several human tumor cell lines. Among these, PM-20 was the most potent with an IC50 of 700 nmol/L for Hep3B human hepatoma cell growth. Two other
Fish & shellfish immunology, 42(2), 503-507 (2014-12-09)
Lectins (carbohydrate-binding proteins) are well known to actively participate in the defense functions of vertebrates and invertebrates where they play an important role in the recognition of foreign particles. In this study, we investigated of in vitro antifungal activity of
BMC cancer, 10, 268-268 (2010-06-10)
High-grade gliomas have poor prognosis, requiring aggressive treatment. The aim of this study is to explore mitotic and centrosomal dysregulation in gliomas, which may provide novel targets for treatment. A case-control study was performed using 34 resected gliomas, which were
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