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Merck

P0105

Sigma-Aldrich

PM-20

≥96% (HPLC), solid

别名:

1-[1,1′-biphenyl]-4-yl-3,4-bis[(2-hydroxyethyl)thio]-1H-Pyrrole-2,5-dione

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About This Item

经验公式(希尔记法):
C20H19NO4S2
分子量:
401.50
MDL號碼:
分類程式碼代碼:
12352200

化驗

≥96% (HPLC)

形狀

solid

顏色

yellow

溶解度

DMSO: >10 mg/mL

儲存溫度

−20°C

SMILES 字串

OCCSC1=C(SCCO)C(=O)N(C1=O)c2ccc(cc2)-c3ccccc3

InChI

1S/C20H19NO4S2/c22-10-12-26-17-18(27-13-11-23)20(25)21(19(17)24)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-9,22-23H,10-13H2

InChI 密鑰

RFZCIUONZTUZER-UHFFFAOYSA-N

生化/生理作用

PM-20 is a Cdc25A phosphatase inhibitor.

注意

air sensitive

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Siddhartha Kar et al.
Molecular cancer therapeutics, 5(6), 1511-1519 (2006-07-05)
We have synthesized several new phenyl maleimide compounds, which are potent growth inhibitors of several human tumor cell lines. Among these, PM-20 was the most potent with an IC50 of 700 nmol/L for Hep3B human hepatoma cell growth. Two other
Irina V Chikalovets et al.
Fish & shellfish immunology, 42(2), 503-507 (2014-12-09)
Lectins (carbohydrate-binding proteins) are well known to actively participate in the defense functions of vertebrates and invertebrates where they play an important role in the recognition of foreign particles. In this study, we investigated of in vitro antifungal activity of
Joon-Khim Loh et al.
BMC cancer, 10, 268-268 (2010-06-10)
High-grade gliomas have poor prognosis, requiring aggressive treatment. The aim of this study is to explore mitotic and centrosomal dysregulation in gliomas, which may provide novel targets for treatment. A case-control study was performed using 34 resected gliomas, which were

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