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P0048

Sigma-Aldrich

匹莫林

≥98% (HPLC)

别名:

2-氨基-5-苯基 4(5H)-噁唑酮, 苯异妥因

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About This Item

经验公式（希尔记法）:
C9H8N2O2
CAS号:
2152-34-3
分子量:
176.17
EC號碼:
218-438-8
MDL號碼:
MFCD00083197
分類程式碼代碼:
12352200
PubChem物質ID:
329819998
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

solid

藥物控制

USDEA Schedule IV; Home Office Schedule 4.2; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

溶解度

DMSO: 28 mg/mL

起源

Boehringer Ingelheim

儲存溫度

2-8°C

SMILES 字串

NC1=NC(=O)C(O1)c2ccccc2

InChI

1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

InChI 密鑰

NRNCYVBFPDDJNE-UHFFFAOYSA-N

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生化／生理作用

匹莫林为中枢神经兴奋剂。匹莫林用于治疗注意缺陷多动障碍 (ADHD)。匹莫林为第 IV 类精神药品，因其不会造成食欲下降或导致口干而比其他兴奋剂具有优势。

特點和優勢

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302 + H312 + H332

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

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Gideon Koren et al.
Handbook of experimental pharmacology, 205, 169-180 (2011-09-02)
It typically takes many years before an association of a drug with a rare, serious adverse reaction is established. As related to pediatric drug use, evidence is even more erratic, as most drugs are used off labels. To enhance child
Carol S Ramsey et al.
Aviation, space, and environmental medicine, 79(8), 769-773 (2008-08-23)
The impact of pharmacological agents on aviators concerns all flight surgeons. This study tested the related hypotheses that acute fatigue reduces +Gz tolerance and endurance, and that stimulants can partially reverse this impact. Additionally, the researchers attempted to develop a
Coming into focus. Pharmacologic treatment for ADHD.
Mary Ann McDonnell et al.
Advance for NPs & PAs, 1(4), 16-22 (2011-02-16)
Pharmacologic treatments for fatigue associated with palliative care.
Marilyn Kirshbaum
Clinical journal of oncology nursing, 15(4), 438-439 (2011-08-04)
Amber M Muehlmann et al.
Behavioural brain research, 189(1), 32-40 (2008-02-05)
Self-injurious behaviour (SIB) is exhibited by individuals with a broad variety of developmental disorders and genetic abnormalities, including autism and Lesch-Nyhan, Prader-Willi and Rett syndromes. Most research has focused on environmental factors that reinforce SIB, and less is known about
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