N6909

Neurturin human

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• 别名: NRTN, NTN
• MDL编号: MFCD01867712
• UNSPSC代码: 51111800

属性

• 生物来源: human
• 重组: expressed in E. coli
• 方案: >95% (SDS-PAGE)
• 表单: lyophilized powder
• 效能: 15-50 ng/mL ED₅₀
• 分子量: monomer calculated mol wt ~12.5 kDa; predicted mol wt ~14 kDa by SDS-PAGE (reducing)
• 储存条件: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• 杂质: endotoxin, tested
• UniProt登记号: Q99748
• 储存温度: −20°C
• 基因信息: human ... NRTN(4902)

说明

生化/生理作用

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways.

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways. Human and mouse NTN share 91% sequence identity.

外形

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

分析说明

The biological activity is measured by its ability to bind recombinant human GFRα2/Fc.

安全信息

• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)