N214

Neutrophil Activating Peptide-2 human

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• 别名: NAP-2
• MDL號碼: MFCD00241917
• 分類程式碼代碼: 51111800

属性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: >97% (SDS-PAGE)
• 形狀: lyophilized powder
• 效力: 0.1-0.3 μg/mL ED₅₀ (cytochalasin B treated human neutrophils); 0.1-0.5 ng/mL ED₅₀ (BaF/3 hCXCR-2 transfected cells)
• 分子量: ~7.6 kDa
• 儲存條件: avoid repeated freeze/thaw cycles (Storage in "frost-free" freezers is not recommended)
• 技術: cell culture | mammalian: suitable
• 雜質: endotoxin, tested
• UniProt登錄號: P02775
• 儲存溫度: −20°C
• 基因資訊: human ... PPBP(5473)

说明

生化／生理作用

Neutrophil Activating Peptide-2, a member of the CXC chemokine family, chemoattracts and activates neutrophils and also binds CXCR-2. NAP-2 is proteolytically processed C-terminal fragments of platelet basic protein (PBP), which is found in the α-granules of human platelets.

外觀

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

分析報告

The biological activity is measured by the induction of myeloperoxidase release from cytochalasin B treated human neutrophils.