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Merck

N1773

Sigma-Aldrich

[Ser2]-Neuromedin C

≥97% (HPLC)

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About This Item

经验公式(希尔记法):
C49H72N16O11S
分子量:
1093.26
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.26

product name

[Ser2]-Neuromedin C, ≥97% (HPLC)

品質等級

化驗

≥97% (HPLC)

形狀

solid

成份

Peptide content, ~70%

UniProt登錄號

儲存溫度

−20°C

SMILES 字串

CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(CO)NC(=O)CN)C(C)C)C(N)=O

InChI

1S/C49H72N16O11S/c1-25(2)13-34(45(72)61-33(42(51)69)11-12-77-6)62-46(73)36(15-29-19-52-23-56-29)59-40(68)21-55-49(76)41(26(3)4)65-43(70)27(5)58-44(71)35(14-28-18-54-32-10-8-7-9-31(28)32)63-47(74)37(16-30-20-53-24-57-30)64-48(75)38(22-66)60-39(67)17-50/h7-10,18-20,23-27,33-38,41,54,66H,11-17,21-22,50H2,1-6H3,(H2,51,69)(H,52,56)(H,53,57)(H,55,76)(H,58,71)(H,59,68)(H,60,67)(H,61,72)(H,62,73)(H,63,74)(H,64,75)(H,65,70)

InChI 密鑰

CDSKUMVQOSVSRF-UHFFFAOYSA-N

基因資訊

human ... GRP(2922)

Amino Acid Sequence

Gly-Ser-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2

生化/生理作用

[Ser2]-Neuromedin C is a bombesin-like peptide known to inhibit feeding.

其他說明

Bombesin-like peptide originally isolated from the brain of the European green frog, Rana ridibunda.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Eva Mónika Fekete et al.
Brain research bulletin, 71(4), 386-392 (2007-01-09)
Bombesin-like peptides including gastrin releasing peptide and neuromedin C are known to inhibit feeding. Bombesin receptors have been found in moderate to high densities in the amygdaloid body, which is essentially involved in the regulation of feeding and body weight.
Biochemical and Biophysical Research Communications, 178, 529-529 (1991)

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