推荐产品
化驗
≥98%
形狀
powder
反應適用性
reagent type: linker
mp
70-73 °C (lit.)
溶解度
chloroform: 100 mg/mL
DMF: soluble (lit.)(lit.)
官能基
NHS ester
儲存溫度
−20°C
SMILES 字串
O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI
1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI 密鑰
VLARLSIGSPVYHX-UHFFFAOYSA-N
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應用
一种插入了具有胺和巯基反应性延长间隔基的异双功能性交联剂。通常,首先通过在pH7.5(6.5-8.5)缓冲的酰胺键与含有伯胺的分子偶联。第二偶联对于通过在pH6.8(6.5-7.0)缓冲的硫醚键而含有游离巯基的分子是特异性的。可用于制备酶免疫耦合物和半抗原载体分子耦合物。包含9个原子连接子。与芳族间隔基相比,延伸的脂族间隔基在偶联之前可稳定马来酰亚胺。
訊號詞
Warning
危險分類
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Journal of clinical microbiology, 34(2), 241-248 (1996-02-01)
Synthetic peptides, derived from the amino acid sequence of a Leishmania donovani clone, were used to develop an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against L. donovani. For this purpose, five peptides were conjugated to a protein carrier, human
International archives of allergy and immunology, 120(3), 199-208 (1999-12-11)
We have previously reported that ovalbumin (OVA) coupled with liposome via glutaraldehyde (GA) induced OVA-specific- and IgE-selective unresponsiveness in mice. In this study, OVA-liposome conjugates were made using four different coupling protocols: via GA, N-(6-maleimidocaproyloxy) succinimide (EMCS), disuccinimidyl suberate (DSS)
Journal of immunological methods, 146(1), 83-90 (1992-01-21)
Recently, the multipin approach for simultaneous multiple peptide synthesis was applied to the analysis of T cell determinants by using a novel cleavage method (Maeji et al., 1990). A diketopiperazine forming linker allowed cleavage of peptides into aqueous buffer which
Journal of applied biochemistry, 6(1-2), 56-63 (1984-02-01)
Nine different maleimide compounds were evaluated for the conjugation of Fab' to horseradish peroxidase through thiol groups in the hinge. The compounds evaluated were succinimidyl maleimidoacetate (I), succinimidyl 4-maleimidobutyrate (II), succinimidyl 6-maleimidohexanoate (III), succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate (IV), succinimidyl m-maleimidobenzoate (V), succinimidyl
Biochemistry, 42(47), 13909-13918 (2003-11-26)
Posttranslational modifications of the endothelin receptors A and B from human lung fibroblasts were investigated before and after stimulation of the cells with (dA)(30)-5'-S-EMC-endothelin-1. The patterns of phosphorylation and palmitoylation of both receptors were much more complicated than expected. In
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