形狀
solid
儲存條件
desiccated
protect from light
under inert gas
顏色
white
溶解度
H2O: ~18 mg/mL
儲存溫度
2-8°C
SMILES 字串
Cl[H].Cl[H].CN(C)Cc1ccccc1Sc2ccc(C)cc2N
InChI
1S/C16H20N2S.2ClH/c1-12-8-9-16(14(17)10-12)19-15-7-5-4-6-13(15)11-18(2)3;;/h4-10H,11,17H2,1-3H3;2*1H
InChI 密鑰
GSBZMNLLLNHKDY-UHFFFAOYSA-N
生化/生理作用
High affinity ligand for the serotonin transporter SERT
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Journal of medicinal chemistry, 45(6), 1253-1258 (2002-03-08)
A series of diphenyl sulfide derivatives substituted at the 1-, 2'-, and 4'-positions has been synthesized and evaluated for their in vitro affinities at the dopamine, serotonin (SERT), and norepinephrine transporters. The examination of K(i) values revealed that most of
The Journal of pharmacology and experimental therapeutics, 304(1), 81-87 (2002-12-20)
Serotonin transporter has a key-role in regulation of serotoninergic function, and is involved in numerous neurodegenerative and psychiatric disorders. To obtain an efficient radioactive ligand allowing the study of this transporter in vitro and in vivo, we synthesized a new
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