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Merck

M6309

Sigma-Aldrich

Anti-Matrix Metalloproteinase-23, Hinge Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

别名:

Anti-MMP-23

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About This Item

MDL编号:
UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous glycerol solution

分子量

antigen (active form) 45 kDa
antigen (pro-form) 58 kDa

种属反应性

human

浓度

~1 mg/mL

技术

immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1:1,000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... MMP14(4323)

一般描述

Matrix metalloproteinase-23B (MMP-23B) possesses regions which are rich in amino acids like proline and cysteine. The MMP-23B gene is localized on human chromosome 1p36.

特异性

Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms.

免疫原

synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).

生化/生理作用

Matrix metalloproteinase-23B (MMP-23B) is part of the matrix metalloproteinase family of proteins, which take part in the remodeling of the extracellular matrix.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marzena Gajecka et al.
European journal of human genetics : EJHG, 13(2), 139-149 (2004-10-16)
Structural chromosome abnormalities have aided in gene identification for over three decades. Delineation of the deletion sizes and rearrangements allows for phenotype/genotype correlations and ultimately assists in gene identification. In this report, we have delineated the precise rearrangements in four
Matrix metalloproteinases.
H Nagase et al.
The Journal of biological chemistry, 274(31), 21491-21494 (1999-07-27)

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