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Merck

M6014

Sigma-Aldrich

Met-Leu-Phe acetate salt

≥97% (HPLC)

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About This Item

经验公式(希尔记法):
C20H31N3O4S
CAS号:
分子量:
409.54
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

方案

≥97% (HPLC)

储存温度

−20°C

SMILES字符串

CSCCC(N)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(O)=O

InChI

1S/C20H31N3O4S/c1-13(2)11-16(22-18(24)15(21)9-10-28-3)19(25)23-17(20(26)27)12-14-7-5-4-6-8-14/h4-8,13,15-17H,9-12,21H2,1-3H3,(H,22,24)(H,23,25)(H,26,27)

InChI key

CHDYFPCQVUOJEB-UHFFFAOYSA-N

质量

Exhibits very weak chemotactic properties.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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Didier G Ebo et al.
Journal of immunological methods, 375(1-2), 30-38 (2011-09-29)
Stimulated human basophils exhibit different degranulation patterns with release of mediators and appearance of activation markers such as CD63 and CD203c. Traditionally, released mediators are quantified in the supernatant of activated cells, whereas the expression of activation markers by individual
S Pontremoli et al.
The Journal of biological chemistry, 265(2), 706-712 (1990-01-15)
Two major protein kinase C (PKC) isozymes, accounting for approximately 95% of the total activity in human neutrophils, were separated by hydroxyapatite chromatography and were identified as beta-PKC (60% of the total) and alpha-PKC (35% of the total). No gamma-PKC
W Tao et al.
The Biochemical journal, 257(3), 633-637 (1989-02-01)
[3H]Arachidonic acid is released after stimulation of rabbit neutrophils with fMet-Leu-Phe or platelet-activating factor (PAF). The release is rapid and dose-dependent, and is inhibited in phorbol 12-myristate 13-acetate (PMA)-treated rabbit neutrophils. The protein kinase C (PKC) inhibitor 1-(5-isoquinoline-sulphonyl)-2-methylpiperazine (H-7) prevents
M A Moseley et al.
Journal of chromatography, 516(1), 167-173 (1990-09-07)
Mixtures of peptides have been analyzed by capillary zone electrophoresis in conjunction with mass spectrometry (MS) using an on-line coaxial continuous-flow fast atom bombardment interface. MS and MS-MS spectra have been acquired in electrophoretic real time from femtomole levels of
S Nigam et al.
Agents and actions. Supplements, 45, 297-301 (1995-01-01)
In the present study, we have shown that the protein kinase C (PKC) inhibition by staurosporine augmented fMet-Leu-Phe-(FMLP)-induced arachidonic acid (AA) release in human polymorph neutrophils (PMN). This effect is in contradiction to a recently reported mechanism that besides Ca2+

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