M3316

Myoseverin B

≥97% (HPLC)

• 别名: 2,6-Bis(4-methoxybenzylamino)-9-cyclohexylpurine
• 经验公式（希尔记法）: C₂₇H₃₂N₆O₂
• CAS号: 361431-27-8
• 分子量: 472.58
• MDL编号: MFCD08276922
• UNSPSC代码: 12352200
• PubChem化学物质编号: 24724538
• NACRES: NA.77

属性

• 方案: ≥97% (HPLC)
• 溶解性: DMSO: soluble; H₂O: insoluble
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C5CCCCC5)c4n2)cc1
• InChI: 1S/C27H32N6O2/c1-34-22-12-8-19(9-13-22)16-28-25-24-26(33(18-30-24)21-6-4-3-5-7-21)32-27(31-25)29-17-20-10-14-23(35-2)15-11-20/h8-15,18,21H,3-7,16-17H2,1-2H3,(H2,28,29,31,32)
• InChI key: ZUZXYJOSNSTJMU-UHFFFAOYSA-N

说明

生化/生理作用

Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. Myoseverin can be effectively used for the inhibition of new vessel growth by inhibiting endothelial cell function and differentiation of progenitor cells.

Tubulin polymerization inhibitor.

安全信息

• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)