推荐产品
品質等級
起源
Boehringer Ingelheim
SMILES 字串
OS(O)(=O)=O.CC(C)NCC(O)c1cc(O)cc(O)c1.CC(C)NCC(O)c2cc(O)cc(O)c2
InChI
1S/2C11H17NO3.H2O4S/c2*1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h2*3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)
InChI 密鑰
MKFFGUZYVNDHIH-UHFFFAOYSA-N
基因資訊
human ... ADRB2(154)
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應用
Metaproterenol hemisulfate salt has been used:
- as a β2-adrenoceptor agonist to study its effects on adenylyl cyclase stimulation in red blood cell deformability
- as an adrenergic agonist to study its effects on the stereoselective cell uptake by organic cation transporters in human embryonic kidney cell lines
- as a bronchodilator to study its effects on the activation of G-protein coupled receptors (GPCR)
生化/生理作用
Metaproterenol is a β2-adrenoceptor agonist. It shows bronchodilator activity and shows therapeutic effects against bronchitis, asthma, and emphysema.
特點和優勢
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Inhalation
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Stimulation by transforming growth factor-α of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: modulation by α- and β-adrenoceptor agonists.
Journal of Pharmacology and Experimental Therapeutics, 29, 171-171 (1999)
Biochemical pharmacology, 54(1), 61-72 (1997-07-01)
We have examined the effect of increased Gs protein levels on the abilities of three different beta2-agonists to induce GTP shifts and stimulate adenylyl cyclase response in an effort to investigate the kinetic association between the beta2-adrenergic receptor Gs and
Journal of chromatographic science, 52(9), 1095-1103 (2013-10-29)
The retention behavior for a series of amine neurotransmitters, their precursors, metabolites and structurally related drugs has been investigated in reversed-phase thin-layer chromatography using RP-18, RP-8, RP-2, CN and Diol stationary phases and mixtures of phosphate buffer and methanol as
Chromatograms
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