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化驗
≥99% (HPLC)
儲存溫度
2-8°C
SMILES 字串
CC1OC(OC(C(NC(C)=O)C=O)C(OC2OC(CO)C(O)C(O)C2O)C(O)CO)C(O)C(O)C1O
InChI
1S/C20H35NO15/c1-6-11(27)13(29)15(31)19(33-6)35-17(8(3-22)21-7(2)25)18(9(26)4-23)36-20-16(32)14(30)12(28)10(5-24)34-20/h3,6,8-20,23-24,26-32H,4-5H2,1-2H3,(H,21,25)
InChI 密鑰
ZAFUNKXZZPSTLA-UHFFFAOYSA-N
生化／生理作用
Lewis-X is a developmentally regulated antigen and has been suggested to be a tumor marker. At high concentrations, it inhibits P-selectin−mediated adhesion.
其他說明
Lewis-X is the trisaccharide part of the sialyl-Lewis-X tetrasaccharide, the suggested ligand for P- and E-selectins.
Wilkins, W.M., et al.
ACS Symp. Ser., 519, 34-34 (1993)
L A Lasky
Science (New York, N.Y.), 258(5084), 964-969 (1992-11-06)
Although a bewildering array of cell surface carbohydrate structures have been described, the physiological relevance of any of these complex molecules has often eluded biologists. A family of cell surface glycoproteins, the "selectins," has a characteristic ability to use some
Marko Haramija et al.
Rapid communications in mass spectrometry : RCM, 31(20), 1709-1719 (2017-08-15)
Affinity mass spectrometry (AMS) is an emerging tool in the field of the study of protein•carbohydrate complexes. However, experimental obstacles and data analysis are preventing faster integration of AMS methods into the glycoscience field. Here we show how analysis of
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