I7026

Anti-Insulin-like Growth Factor Binding Protein-4 antibody produced in goat

affinity isolated antibody, lyophilized powder

• 别名: Anti-IGFBP-4
• MDL编号: MFCD01633492
• UNSPSC代码: 51111800

属性

• 生物来源: goat
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: lyophilized powder
• 种属反应性: human
• 技术: indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt登记号: P22692
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... IGFBP4(3487)

说明

一般描述

Insulin-like growth factor binding protein-4 (IGFBP-4) is a 26kD (approx.) protein expressed highly in non-paranchymal cells of the liver. IGFBP-4 is also expressed in spleen, liver, lung, kidney, adrenal, testis, heart, brain cortex, stomach and hypothalamus. It has a pivotal role in protecting cells from overstimulation caused by IGFs or towards activating the alternate transmembrane signaling pathways that are inhibited by IGF exposure. Anti-Insulin-like Growth Factor Binding Protein 4(IGFBP-4) antibody can be used in western blotting. Goat anti-IGFBP-4 antibody reacts specifically with recombinant human IGFBP-4. The product has shown no cross-reactivity for recombinant human IGFBP-1, recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-5 and recombinant human IGFBP-6.

特异性

By immunoblotting and ELISA, the antibody show no cross-reactivity with recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-1, recombinant human IGFBP-5, and recombinant human IGFBP-6.

免疫原

purified, NSO-derived, recombinant human insulin-like growth factor binding protein 4.

应用

Anti-Insulin-like Growth Factor Binding Protein-4(IGFBP-4) antibody can be used in neutralization and indirect ELISA.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.