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生物源
synthetic (organic)
化驗
≥99% (HPLC)
形狀
powder
溶解度
water: 50 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
NC1=NC(=O)N(C=C1I)[C@H]2C[C@@H](O)[C@H](CO)O2
InChI
1S/C9H12IN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5?,6?,7-/m1/s1
InChI 密鑰
WEVJJMPVVFNAHZ-KPGICGJXSA-N
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應用
5-Iodo-2′-deoxycytidine (5-iododeoxycytidine) is used in the construction of DNA oligomers to enable structural studies and photoactivated cross-linking. 5-Iodo-2′-deoxycytidine is used in the synthesis of other modified nucleosides, such as 5-ethynylferrocenyl-2′-deoxycytidine used in semiconductor electrodes and 10-(2-deoxyβ-D-ribofuranosyl)pyrimido[4′,5′:4,5]pyrimido[1,6-a]indole-6,9(7H)-dione (dCPPI).
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
S A Koch et al.
Pharmaceutical research, 4(4), 317-320 (1987-08-01)
Two Mannich-base prodrugs of 5-iodo-2'-deoxycytidine (5-IDC) have been synthesized. The prodrugs exhibit increased lipid solubility compared to 5-IDC and rapidly revert to 5-IDC in buffer. One of the prodrugs delivered about twice as much 5-IDC from isopropyl myristate (IPM) through
R J DuFrain
Basic life sciences, 29 Pt A, 41-58 (1984-01-01)
This communication describes the use of 6 different halogenated pyrimidine analogues, bromodeoxyuridine (BrdUrd), chlorodeoxyuridine (CldUrd), iododeoxyuridine (IdUrd), bromodeoxycytidine (BrdCyd), chlorodeoxycytidine (CldCyd), and iododeoxycytidine (IdCyd), to achieve sister chromatid differentiation (SCD) and evaluate sister chromatid exchange (SCE) formation in mitogen-stimulated human
D Sincholle et al.
Current eye research, 4(5), 627-629 (1985-05-01)
The study of the permeability of the cornea to 5-iodo-2'-deoxycytidine (IDC), an antiherpetic agent was performed in the rabbit. In a first experiment, using 125I-IDC eye-drops and a sustained contact between the drug and the cornea, we showed that the
P W Hammond et al.
Molecular and cellular biology, 17(1), 296-308 (1997-01-01)
Telomerase is a ribonucleoprotein enzyme that adds telomeric sequence repeats to the ends of linear chromosomes. In vitro, telomerase has been observed to add repeats to a DNA oligonucleotide primer in a processive manner, leading to the postulation of a
[Superficial herpetic keratitis: comparative double-blind treatment with iododeoxycytidine and acyclovir].
J Colin
Bulletin des societes d'ophtalmologie de France, 84(11), 1283-1286 (1984-11-01)
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