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Merck

I151

Sigma-Aldrich

Indomethacin morpholinylamide

solid

别名:

BML-190, N-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetyl]morpholine

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About This Item

经验公式(希尔记法):
C23H23ClN2O4
分子量:
426.89
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

solid

顏色

off-white

溶解度

DMSO: >20 mg/mL
H2O: insoluble

儲存溫度

2-8°C

SMILES 字串

COc1ccc2n(c(C)c(CC(=O)N3CCOCC3)c2c1)C(=O)c4ccc(Cl)cc4

InChI

1S/C23H23ClN2O4/c1-15-19(14-22(27)25-9-11-30-12-10-25)20-13-18(29-2)7-8-21(20)26(15)23(28)16-3-5-17(24)6-4-16/h3-8,13H,9-12,14H2,1-2H3

InChI 密鑰

BJSDNVVWJYDOLK-UHFFFAOYSA-N

基因資訊

human ... CNR2(1269)

生化/生理作用

CB2 cannabinoid receptor agonist.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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E Romeo et al.
The Journal of pharmacology and experimental therapeutics, 262(3), 971-978 (1992-09-01)
The 2 aryl-3-indoleacetamides (FGIN-1) are a new class of compounds that potently (nM) and selectively bind to glial mitochondrial diazepam binding inhibitor (DBI) receptors (MDR), previously called peripheral benzodiazepine receptors, and increase mitochondrial steroidogenesis. The high-affinity binding of FGIN-1 to
Pretal P Muldoon et al.
Neuropharmacology, 176, 108170-108170 (2020-06-02)
Nicotine, the primary psychoactive component in tobacco, plays a major role in the initiation and maintenance of tobacco dependence and addiction, a leading cause of preventable death worldwide. An essential need thus exists for more effective pharmacotherapies for nicotine-use cessation.

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