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蒸汽密度
3 (vs air)
蒸汽壓力
1.5 mmHg ( 20 °C)
化驗
≥99% (GC)
自燃溫度
851 °F
expl. lim.
16 %
折射率
n20/D 1.436 (lit.)
bp
204-205 °C (lit.)
mp
−45 °C (lit.)
密度
1.12 g/mL at 25 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
O=C1CCCO1
InChI
1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
InChI 密鑰
YEJRWHAVMIAJKC-UHFFFAOYSA-N
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生化／生理作用
γ-羟基丁酸(GHB)前体。 可通过阻断多巴胺能神经元的脉冲流，抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
208.4 °F - closed cup
閃點（°C）
98 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Michelle Wood et al.
Journal of chromatography. A, 1056(1-2), 83-90 (2004-12-15)
We have developed a rapid method that enables the simultaneous analysis of gamma-hydroxybutyrate (GHB) and its precursors, i.e. gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in urine. The method comprised a simple dilution of the urine sample, followed by liquid chromatography-tandem mass
Zheng-Yuan Su et al.
Chemical research in toxicology, 26(3), 477-485 (2013-02-28)
Cancer development has been linked to epigenetic modifications of cancer oncogenes and tumor suppressor genes; in advanced metastatic cancers, severe epigenetic modifications are present. We previously demonstrated that the progression of prostate tumors in TRAMP mice is associated with methylation
Christian Westendorf et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3853-3858 (2013-02-23)
The rapid reorganization of the actin cytoskeleton in response to external stimuli is an essential property of many motile eukaryotic cells. Here, we report evidence that the actin machinery of chemotactic Dictyostelium cells operates close to an oscillatory instability. When
Bo Xue et al.
Biochemistry, 52(13), 2359-2370 (2013-03-07)
The in vitro evolution and engineering of quorum-quenching lactonases with enhanced reactivities was achieved using a thermostable GKL enzyme as a template, yielding the E101G/R230C GKL mutant with increased catalytic activity and a broadened substrate range [Chow, J. Y., Xue
Axel Bidon-Chanal et al.
European journal of medicinal chemistry, 60, 479-489 (2013-01-29)
Glycogen synthase kinase 3β (GSK-3β) is widely recognised as a relevant player in the pathogenesis of several highly prevalent disorders such as Alzheimer's disease, mood disorders, diabetes and cancer. Therefore, this enzyme constitutes a highly attractive therapeutic target for the
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