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Merck

H5520

Sigma-Aldrich

17α-己酸羟孕酮

≥98%

别名:

17α-Hydroxyprogesterone caproate

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About This Item

经验公式(希尔记法):
C27H40O4
CAS号:
分子量:
428.60
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

化驗

≥98%

SMILES 字串

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(=O)CCCCC)C(C)=O

InChI

1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1

InChI 密鑰

DOMWKUIIPQCAJU-LJHIYBGHSA-N

基因資訊

human ... PGR(5241)

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生化/生理作用

Shows significant reduction of pre-term delivery by mothers with a history of premature delivery, with no detectable harm to the infant.

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Faris Mujezinovic et al.
The Cochrane database of systematic reviews, 8(8), CD008678-CD008678 (2012-08-17)
Currently, the techniques for amniocentesis and chorionic villus sampling (CVS) tend to be described in local and national guidelines, but certain aspects, including the choice of instruments, is predominantly based upon the operator's personal preference. A survey of practice in
Steve N Caritis et al.
American journal of obstetrics and gynecology, 208(6), 470-470 (2013-03-05)
17-alpha hydroxyprogesterone caproate (17-OHPC) is available both as an Food and Drug Administration (FDA)-approved medication and as a product prepared for individual patients by compounding pharmacies. Compounding pharmacies may omit the preservative that is used in the FDA-approved formulation or
Shringi Sharma et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(2), 296-304 (2012-11-07)
Little information is available in the literature regarding the expression and activity of transporters in fetal human liver or cultured cells. A synthetic progesterone structural analog, 17α-hydroxyprogesterone caproate (17-OHPC), is used in the prevention of spontaneous abortion in women with
A C Lim et al.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 40(4), 426-430 (2012-09-26)
Previous studies on singleton pregnancies have indicated that progestogens may reduce the rate of cervical shortening during pregnancy. The aim of this study was to investigate whether treatment with 17-alpha hydroxyprogesterone caproate (17-OHPC) has an effect on cervical shortening in
Courtney D Cuppett et al.
American journal of obstetrics and gynecology, 208(1), 86-86 (2012-10-16)
Plasma concentrations of 17-alpha-hydroxyprogesterone caproate (17-OHPC) vary substantially in pregnant patients who receive an identical dose. Endogenous steroid hormones may alter 17-OHPC metabolism, which contributes to this large variability. Pooled human liver microsomes were incubated with 17-OHPC alone or in

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