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生物源
chicken
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
rat, mouse, human
製造商／商標名
Genway 15-288-22778
技術
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... GSK3A(2931)
免疫原
Immunogen Sequence: GI # 11995474, sequence 89-100
Synthetic peptide sequence of glycogen synthase kinase 3α.
應用
Anti-GSK3α antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化／生理作用
Glycogen synthase kinase-3α is an enzyme encoded by the GSK3A gene in humans and is located on chromosome 19q13.2. It is a serine-threonine kinase that exists as two isoforms, α and β. GSK-3α is widely expressed throughout the follicles and plays a role in cancer development such as acute myeloid leukemia (AML). It is an important component of the therapeutic actions of drugs used to treat mood disorders and can be a potential target for developing new therapeutic interventions.
外觀
Solution in phosphate buffered saline containing 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Xiaohua Li et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(11), 2143-2154 (2010-07-30)
Little is known regarding the mechanisms underlying the complex etiology of mood disorders, represented mainly by major depressive disorder and bipolar disorder. The 1996 discovery that lithium inhibits glycogen synthase kinase-3 (GSK3) raised the possibility that impaired inhibition of GSK3
Koichi Yamauchi et al.
Archives of dermatological research, 302(4), 263-270 (2009-08-26)
Beta-catenin is involved in the hair follicle morphogenesis and stem cell differentiation, and inhibition of glycogen synthase kinase-3 (GSK-3) increases beta-catenin concentration in the cytoplasm. To examine the effects of GSK-3 inhibition on the hair follicle epithelium, we first examined
P C Shaw et al.
Genome, 41(5), 720-727 (1998-11-11)
Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase that exists as two isoforms, alpha and beta, encoded by separate genes. Phosphorylation targets include a variety of cytoplasmic and nuclear proteins. Recent studies found that neurofilaments, amyloid precursor protein, and tau
Versha Banerji et al.
The Journal of clinical investigation, 122(3), 935-947 (2012-02-14)
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults. Long-term survival of patients with AML has changed little over the past decade, necessitating the identification and validation of new AML targets. Integration of genomic approaches
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