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Merck

GE17-5481-51

HiTrap® Capto Core 700

Cytiva 17-5481-51, pack of 5 × 1 mL

别名:

Capto Core 700 Column

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About This Item

分類程式碼代碼:
23151817
NACRES:
NA.56

ligand

octylamine

包裝

pack of 5 × 1 mL

製造商/商標名

Cytiva 17-5481-51

參數

5 bar

柱內徑

7 mm

基質

highly cross-linked agarose

樣品平均尺寸

75 (d₅₀v is the median particle size of the cumulative volume distribution)

cleaning

3-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)

工作範圍

2-14(pH interval where the medium can be operated without significant change in function.)

容量

~13 mg binding capacity (ovalbumin)

適合性

suitable for bioprocess medium

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一般說明

Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 ml/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess resin for intermediate purification and polishing of viruses and other large biomolecules. Capto Core 700 is a novel, layered bead chromatography resin consisting of a porous outer layer and ligand-activated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

特點和優勢

  • High capacity and productivity in flowthrough mode.
  • Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
  • Wide operational window of pH and conductivity.

儲存和穩定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

法律資訊

Capto is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva

象形圖

Flame

訊號詞

Warning

危險聲明

儲存類別代碼

3 - Flammable liquids


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实验方案

This page covers detailed information on cleaning procedures and recommended flow for column cleaning.

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