F1305

Anti-FEN-1 (C-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• 别名: Anti-Flap endonuclease, Anti-Flap structure-specific endonuclease 1
• MDL號碼: MFCD09039190
• 分類程式碼代碼: 12352203

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 45 kDa
• 物種活性: human
• 濃度: ~1 mg/mL
• 技術: immunoprecipitation (IP): 2-4 μg using HEK 293T cell lysates; indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK 293T cells; western blot: 0.5-1 μg/mL using K562 cell lysates
• UniProt登錄號: P39748
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 基因資訊: human ... FEN1(2237) ; mouse ... Fen1(14156) ; rat ... Fen1(84490)

说明

免疫原

synthetic peptide corresponding to amino acids 367-380 of human FEN-1, conjugated to KLH via an N-terminal added cysteine residue. The corresponding sequence in rat and mouse differs by one and two amino acids, respectively.

標靶描述

FEN-1 (C-terminal) encodes a protein that removes 5′ overhanging flaps in DNA repair and processes the 5′ ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch b

外觀

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)