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Merck
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Key Documents

EHU081311

Sigma-Aldrich

MISSION® esiRNA

targeting human NEIL1

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GCCCTATGTTTCGTGGACATCCGCCGGTTCGGCCGCTGGGACCTTGGGGGAAAGTGGCAGCCGGGCCGCGGGCCCTGTGTCTTGCAGGAGTACCAGCAGTTCAGGGAGAATGTGCTACGAAACCTAGCGGATAAGGCCTTTGACCGGCCCATCTGCGAGGCCCTCCTGGACCAGAGGTTCTTCAATGGCATTGGCAACTATCTGCGGGCAGAGATCCTGTACCGGCTGAAGATCCCCCCCTTTGAGAAGGCCCGCTCGGTCCTGGAGGCCCTGCAGCAGCACAGGCCGAGCCCGGAGCTGACCCTGAGCCAGAAGATAAGGACCAAGCTGCAGAATCCAGACCTGCTGGAGCTATGTCACTCAGTGCCCAAGGAAGTGGTCCAGTTGGGGGGCAAAGGCTACGGGTCAGAGAGCGGGGAGGAGGACTTTGCTGCCTTT

Ensembl | 人類登錄號

ENSG00000140398

NCBI登錄號

NM_024608

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... NEIL1(79661) , NEIL1(79661)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Wanjuan Xue et al.
BioMed research international, 2020, 5053975-5053975 (2020-07-21)
The study is aimed at investigating the role of Nei endonuclease VIII-like1 (NEIL1) in the pathogenesis of colorectal cancer (CRC). The human CRC (HCT116 and SW480) cells were subjected to the siRNA silencing and recombinant plasmid overexpression of NEIL1. Transfection
Shiladitya Sengupta et al.
DNA repair, 66-67, 1-10 (2018-04-27)
Posttranslational modifications of DNA repair proteins have been linked to their function. However, it is not clear if posttranslational acetylation affects subcellular localization of these enzymes. Here, we show that the human DNA glycosylase NEIL1, which is involved in repair

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