所有图片(2)
About This Item
经验公式（希尔记法）:
C20H26O3
CAS号:
分子量:
314.42
Beilstein:
2625732
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
無菌
non-sterile
化驗
≥99%
形狀
powder
溶解度
chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow
運輸包裝
ambient
儲存溫度
room temp
SMILES 字串
CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C
InChI
1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1
InChI 密鑰
QAHOQNJVHDHYRN-SLHNCBLASA-N
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應用
β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.
生化／生理作用
β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.
特點和優勢
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
訊號詞
Danger
危險聲明
危險分類
Aquatic Chronic 1 - Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
Bioactive Natural Products: Chemistry and Biology, 375-375 (2015)
Layer-by-Layer Films for Biomedical Applications, 517-517 (2014)
Estrogen and the Vessel Wall, 38-38 (2003)
B H Berg
Biochemistry international, 24(3), 527-533 (1991-06-01)
Adenylyl cyclase activity in the uterus of ovariectomized NMRI mice showed an increase of 87% four minutes after intraperitoneal administration of 17-beta-estradiol 17-beta-acetate in water solution, while in the liver of the same animals activity had decreased by 57%. At
Tomohiro Hikima et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 54(2), 155-160 (2002-08-23)
We have investigated the distribution of hydrolytic enzymes which metabolize beta-estradiol 17-acetate (EA) to beta-estradiol (E) in man and animal skins in vitro. The distribution of hydrolytic enzymes in human cadaver, hairless dog, rat and hairless mouse skin, was investigated
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