E3031

Monoclonal Anti-dEGF Receptor, Cytoplasmic Domain antibody produced in mouse

~1.5 mg/mL, clone E-257, purified immunoglobulin, buffered aqueous solution

• 别名: Anti-Drosophila Epidermal Growth Factor Receptor, Anti-dEGFR
• MDL编号: MFCD08705582
• UNSPSC代码: 51111800

属性

• 生物来源: mouse
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• 抗体产品类型: primary antibodies
• 克隆: E-257, monoclonal
• 表单: buffered aqueous solution
• 种属反应性: Drosophila
• 浓度: ~1.5 mg/mL
• 技术: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: 0.25-0.5 μg/mL using recombinant cytoplasmic domain fragment of the Drosophila EGFR (amino acids 1200-1267)
• 同位素/亚型: IgG1
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: Drosophila melanogaster ... Egfr(37455)

说明

一般描述

The signalling by dEGFR (also known as Torpedo or DER) is crucial for the development processes in Drosophila. The dEGFR signalling results in the activation of the canonical RAS/RAF/MEK/MAPK cascade. A variety of modulators such as Gro, TGF-α, Argos, Sprouty and Notch play an integrative role in EGFR signalling. The other pathways EGFR is involved in the development of the compound eye, larval, eye, wing and malphigian tubule development. Monoclonal Anti-dEGFR, Cytoplasmic Domain recognizes Drosophila Epidermal Growth Factor Receptor (EGFR). The antibody epitope resides within amino acids 1200-1267 of Drosophila EGFR.

免疫原

recombinant cytoplasmic domain fragment of the Drosophila EGFR (amino acids 1200-1267).

应用

Anti-dEGF Receptor, Cytoplasmic Domain antibody may be used for immunoblotting at a working concentration of 0.25-0.5 μg/ml. The antibody is suitable for immunohistochemistry and ELISA.

外形

Solution in 0.01 M phosphate buffered saline containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.