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Merck

D7690

Sigma-Aldrich

Monoclonal Anti-DNA Ligase I antibody produced in mouse

~1 mg/mL, clone 1A9, purified immunoglobulin, buffered aqueous solution

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1A9, monoclonal

形狀

buffered aqueous solution

分子量

antigen ~125 kDa

物種活性

bovine, human

濃度

~1 mg/mL

技術

direct ELISA: suitable
western blot: 1-5 μg/mL using HeLa or DiFi cells

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... LIG1(3978)

一般說明

DNA ligase I is composed of a 78kDa carboxyl-terminal catalytic domain and a 24kDa amino-terminal region.

免疫原

bovine DNA ligase I.

應用

Monoclonal Anti-DNA Ligase I antibody produced in mouse is suitable for direct ELISA and western blot at a working concentration of 1-5μg/mL using HeLa or DiFi cells.

外觀

Solution in phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids


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分析证书(COA)

Lot/Batch Number

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V J Mackenney et al.
The Journal of biological chemistry, 272(17), 11550-11556 (1997-04-25)
The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is believed to be due to DNA ligase I. This enzyme is composed of a 78-kDa carboxyl-terminal catalytic domain and a 24-kDa amino-terminal region that is not

商品

DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.

DNA损伤和修复机制对于维持DNA完整性至关重要。细胞DNA的损伤与突变、癌症发展等有关。

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

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