药品控制
USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
veterinary
包装形式
neat
SMILES字符串
Clc1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1
InChI
1S/C15H10Cl2N2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
InChI key
CHIFCDOIPRCHCF-UHFFFAOYSA-N
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应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
I Bertin et al.
International journal of clinical pharmacology research, 9(3), 203-208 (1989-01-01)
Chlordesmethyldiazepam a long-acting benzodiazepine was compared with lorazepam a short-acting one in a double-blind placebo cross-over study against generalized anxiety disorders. Chlordesmethyldiazepam therapy was more effective than lorazepam. Clinical efficacy, drowsiness and insomnia seem well correlated with pharmacokinetic properties of
J Sennesael et al.
European journal of clinical pharmacology, 41(1), 65-68 (1991-01-01)
The pharmacokinetics of a single 2 mg IV dose of chlordesmethyldiazepam has been studied in 11 patients with renal failure on regular haemodialysis and in 11 age-matched healthy controls. The kinetics was also examined after a single 2 mg oral
P Rocca et al.
Acta psychiatrica Scandinavica, 95(5), 444-450 (1997-05-01)
Recently, there has been a renewed interest in alternatives to the benzodiazepines for the treatment of generalized anxiety disorder (GAD). The aim of the present study was to compare the efficacy of paroxetine vs. imipramine and 2'-chlordesmethyldiazepam in 81 patients
S R Bareggi et al.
European journal of clinical pharmacology, 48(3-4), 265-268 (1995-01-01)
We studied the pharmacokinetics of a single 0.5-mg i.v. dose of chlordesmethyldiazepam in 8 patients with liver disease and in 12 age-matched healthy controls. The kinetics were also studied of a single 1-mg oral dose in the patients with liver
[A ketamine-chlordemethyldiazepam combination in celioscopy].
E Struzziero et al.
Minerva ginecologica, 40(12), 715-717 (1988-12-01)
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