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Merck

D6148

Sigma-Aldrich

二亚乙基三胺五乙酸二酐

别名:

DTPA 二酐, DTPA 酸酐

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25MG
JP¥24,200

JP¥24,200


预计发货时间2025年3月28日



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25MG
JP¥24,200

About This Item

经验公式(希尔记法):
C14H19N3O8
CAS号:
分子量:
357.32
Beilstein:
1230954
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:

JP¥24,200


预计发货时间2025年3月28日


儲存溫度

−20°C

SMILES 字串

OC(=O)CN(CCN1CC(=O)OC(=O)C1)CCN2CC(=O)OC(=O)C2

InChI

1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)

InChI 密鑰

RAZLJUXJEOEYAM-UHFFFAOYSA-N

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應用

向蛋白质引入强效螯合剂的试剂。

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说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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B M Kinsey et al.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 15(3), 285-292 (1988-01-01)
We have developed a simple, rapid, and reproducible method for conjugating the bifunctional metal chelator diethylenetriaminepentaacetic acid (DTPA) to an IgM monoclonal antibody (MoAb) without first isolating the MoAb from the ascites fluid. Treatment of the protein mixture in the
C H Paik et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 24(12), 1158-1163 (1983-12-01)
Diethylenetriaminepentaacetic acid (DTPA) was conjugated with a practical concentration (300 micrograms/ml) of antibody to human albumin (Ab) and 1083 17-1A monoclonal colorectal antibody (MAb-17-1A) via an acylation reaction using cyclic DTPA anhydride (cDTPAA). The conjugation reaction was favored as pH
M Hartikka et al.
European journal of nuclear medicine, 15(3), 157-161 (1989-01-01)
F(ab')2 fragments (at concentrations of 5-30 mg/ml) derived from monoclonal antibodies raised against human prostate specific acid phosphatase were derivatized with a bicyclic anhydride of diethylenetriaminepentaacetic acid (cDTPAA) in the molar ratios of cDTPAA/F(ab')2 of 1:1, 5:1, 10:1 or 50:1.
Chad R Haney et al.
Biochimica et biophysica acta, 1725(3), 358-369 (2005-08-17)
The purpose of this study was to prepare a novel polymerized hemoglobin (Hb) based oxygen carrier (HBOC) designed to minimize Hb induced hypertension, while employing a simple and inexpensive method of preparation. Cyclic-diethylenetriaminepentaacetic acid (DTPA) was used to polymerize stroma
M Perälä et al.
European journal of nuclear medicine, 16(8-10), 621-626 (1990-01-01)
In this study we examined optimization of derivatization of monoclonal antibodies and their fragments intended for use as radiopharmaceutical in radioimaging and/or radioimmunotherapy of prostatic cancer. Two different principles were used to conjugate diethylenetriaminepentaacetic acid (DTPA) to a monoclonal antibody

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