D1814

Anti-DcR3 antibody produced in rabbit

~0.5 mg/mL, IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-Decoy Receptor 3, Anti-TNFRSF6B, Anti-TR6
• MDL编号: MFCD02686088
• UNSPSC代码: 12352203

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: IgG fraction of antiserum
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: antigen 33 kDa
• 种属反应性: mouse, rat, human
• 浓度: ~0.5 mg/mL
• 技术: microarray: suitable; western blot: 1:500-1:1,000 using human heart, brain or kidney lysates
• UniProt登记号: O95407
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... TNFRSF6B(8771) ; mouse ... Dcr3(497118)

说明

一般描述

It is a member of the tumor necrosis factor receptor superfamily (TR6). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

免疫原

synthetic peptide corresponding to amino acids 31-46 of human DcR3 precursor.

应用

Anti-DcR3 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1000 using human heart, brain or kidney lysates.

生化/生理作用

DcR3 is a soluble decoy receptor that binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis.

外形

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.