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化驗
≥95% (HPLC)
形狀
film
成份
Peptide content, ≥60%
顏色
colorless to white
溶解度
H2O: 0.5 mg/mL, clear
運輸包裝
wet ice
儲存溫度
−20°C
Amino Acid Sequence
Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His-NH2
生化／生理作用
Cell permeable cGMP protein kinase (PKG) inhibitor
特點和優勢
This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Mark S Taylor et al.
Molecular pharmacology, 65(5), 1111-1119 (2004-04-23)
Cyclic GMP-dependent protein kinase (PKG) serves as an important physiological regulator of vascular reactivity and tone. However, available inhibitors of PKG have exhibited variable effects in intact tissue, hindering the elucidation of the functional role of PKG in blood vessels.
W R Dostmann et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(26), 14772-14777 (2000-12-20)
Arrays of octameric peptide libraries on cellulose paper were screened by using (32)P-autophosphorylated cGMP-dependent protein kinase Ialpha (cGPK) to identify peptide sequences with high binding affinity for cGPK. Iterative deconvolution of every amino acid position in the peptides identified the
Christin Christensen et al.
Stem cells and development, 15(5), 647-654 (2006-11-16)
Previously, we have shown that increasing the intracellular cGMP concentration enhances the sonic hedgehog (Shh) response in neural plate cells. The use of two mouse embryonic stem (ES) cell lines allowed a highly sensitive and reproducible quantification of the Shh
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