SMILES字符串
OCC1OC(C(O)C1O)n2cnc3c(NC4CCCC4)cc(Cl)nc23
InChI
1S/C16H21ClN4O4/c17-11-5-9(19-8-3-1-2-4-8)12-15(20-11)21(7-18-12)16-14(24)13(23)10(6-22)25-16/h5,7-8,10,13-14,16,22-24H,1-4,6H2,(H,19,20)
InChI key
ZQSTWOIIMKNFPE-UHFFFAOYSA-N
生化/生理作用
A selective A1 adenosine receptor agonist
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Bin Yu et al.
BMC genomics, 19(1), 478-478 (2018-06-20)
Apoptosis is associated with some human diseases, including cancer, autoimmune disease, neurodegenerative disease and ischemic damage, etc. Apoptosis proteins subcellular localization information is very important for understanding the mechanism of programmed cell death and the development of drugs. Therefore, the
Nam D Nguyen et al.
PLoS computational biology, 16(4), e1007677-e1007677 (2020-04-03)
The molecular mechanisms and functions in complex biological systems currently remain elusive. Recent high-throughput techniques, such as next-generation sequencing, have generated a wide variety of multiomics datasets that enable the identification of biological functions and mechanisms via multiple facets. However
C Cano et al.
The Journal of pharmacology and experimental therapeutics, 261(2), 660-668 (1992-05-01)
The subtype of adenosine receptor linked to cardiac prostacyclin (PGI2) synthesis, measured as immunoreactive 6-keto-PGF1 alpha, was investigated in the rabbit heart perfused with Krebs' buffer at 20 ml/min. Adenosine (6.4-50 nmol) decreased 6-keto-PGF1 alpha synthesis, coronary perfusion pressure (PP)
E A van Schaick et al.
Naunyn-Schmiedeberg's archives of pharmacology, 356(6), 827-837 (1998-02-07)
In this study we investigated the relationship between the pharmacokinetics and the cardiovascular and electroencephalogram (EEG) effects of three adenosine agonists with differing lipophilicity. Conscious normotensive rats received either 600 microg/kg N6-(p-sulphophenyl) adenosine (SPA), 200 microg/kg N6-cyclopentyladenosine (CPA) or 600
M S Dar
Pharmacology, biochemistry, and behavior, 37(4), 747-753 (1990-12-01)
To further investigate if the modulation of ethanol-induced motor incoordination is by brain adenosine A1 and/or A2 receptor, adenosine analogs with wide variability in their affinity for A1 and A2 subtypes were administered ICV and their effect on ethanol-induced (IP)
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