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product name
I 型胶原蛋白 −FITC 共轭物 来源于牛皮, ~1 mg/mL, solution
生物源
bovine skin
品質等級
形狀
solution
濃度
~1 mg/mL
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
cow ... COL1A1(282187) , COL1A2(282188)
human ... MMP1 (includes EG:4312)
mouse ... MMP1 (includes EG:4312)
rat ... MMP1 (includes EG:4312)
一般說明
I型胶原蛋白是肌腱和骨骼的主要胶原蛋白，但广泛分布于其他组织，例如皮肤、角膜、牙本质、心脏瓣膜、肺、肝、筋膜和疤痕组织。
應用
来自牛皮肤的I型胶原蛋白FITC共轭物已被用于I型胶原蛋白凝胶变形分析。它也已被用于涂覆硅弹性膜，以用于多种实验研究的细胞接种。它也可用作检测细胞培养物中哺乳动物胶原酶活性的底物。
生化／生理作用
胶原蛋白I提供了机械稳定性，为多种器官，筋，韧带，皮肤，角膜，骨骼和牙本质提供了力量和坚固性。
外觀
以 0.01M 乙酸形式提供。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Faceshields, Gloves, Goggles
Live free or die: Stretch-induced apoptosis occurs when adaptive reorientation of annulus fibrosus cells is restricted
Abbott RD, et al.
Biochemical and Biophysical Research Communications, 421(2), 361-366 (2012)
Ayodele Olaolu Oladejo et al.
Journal of inflammation research, 15, 807-825 (2022-02-18)
Endometritis is a female reproductive disease that affects the cattle industries development and microRNAs (miRNAs) play a pivotal role and critical regulators of the innate immune response in varieties of diseases. The present study intends to investigate the regulatory role
Sjors Maassen et al.
Free radical biology & medicine, 188, 287-297 (2022-06-27)
5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is unclear. Here, we show by
F Nelson et al.
The Journal of clinical investigation, 102(12), 2115-2125 (1998-12-17)
There is evidence to suggest that the synthesis of type II collagen is increased in osteoarthritis (OA). Using an immunoassay, we show that the content of the C-propeptide of type II procollagen (CPII), released extracellularly from the newly synthesized molecule
Benjamin C U Tai et al.
Biomaterials, 31(23), 5927-5935 (2010-05-18)
The paradigm of scaffold tissue engineering relies on the provision of an appropriate environment for cell growth, which includes both structural support and the presentation of cellular signals. In terms of biosignal presentation, fibrous scaffolds by interfacial polyelectrolyte complexation (IPC)
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