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Merck
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主要文件

C4241

Sigma-Aldrich

Anti-Corticotropin-Releasing Factor Receptor 2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-CRFR2

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About This Item

MDL编号:
UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4 μg/mL using human pituitary tissue

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CRHR2(1395)
mouse ... Crhr2(12922)
rat ... Crhr2(64680)

免疫原

synthetic peptide corresponding to the extracellular N-terminal domain of human corticotropin-releasing factor receptor, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.

外形

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Shaaban A Mousa et al.
Molecular neurobiology, 58(11), 5459-5472 (2021-08-01)
Corticotropin-releasing factor (CRF) orchestrates our body's response to stressful stimuli. Pain is often stressful and counterbalanced by activation of CRF receptors along the nociceptive pathway, although the involvement of the CRF receptor subtypes 1 and/or 2 (CRF-R1 and CRF-R2, respectively)
Shaaban A Mousa et al.
Journal of neuroinflammation, 19(1), 148-148 (2022-06-16)
Under inflammatory conditions, the activation of corticotropin-releasing factor (CRF) receptor has been shown to inhibit pain through opioid peptide release from immune cells or neurons. CRF's effects on human and animal pain modulation depend, however, on the distribution of its

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