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Merck

C3366

Sigma-Aldrich

Anti-CXCR5 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-CXC Chemokine Receptor 5

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About This Item

MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5 μg/mL using human lymph node, B-cell lymphoma

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CXCR5(643)
mouse ... Cxcr5(12145)
rat ... Cxcr5(29363)

免疫原

synthetic peptide corresponding to the C-terminus of human CXC chemokine receptor 5 (CXCR5), conjugated to KLH. The immunizing peptide has 94% homology with the rat gene and 100% homology with the mouse gene.

生化/生理作用

CXCR5 is a multi-pass membrane protein expressed in mature B cells. It binds to B-lymphocyte chemoattractant and regulates the migration of B cells. The expression of CXCR5 is important for CD4 T cell-mediated humoral immune responses.

外觀

Solution in PBS, 0.1% Sodium Azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Through the looking glass: the diverse in vivo activities of chemokines.
S L Kunkel
The Journal of clinical investigation, 104(10), 1333-1334 (1999-11-24)
Nina Chevalier et al.
Journal of immunology (Baltimore, Md. : 1950), 186(10), 5556-5568 (2011-04-08)
High expression of CXCR5 is one of the defining hallmarks of T follicular helper cells (T(FH)), a CD4 Th cell subset that promotes germinal center reactions and the selection and affinity maturation of B cells. CXCR5 is also expressed on

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