C2854

Caspase 2 human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution, >1000 units/mg protein

• 别名: Ich-1, Nedd2
• MDL编号: MFCD02686998
• UNSPSC代码: 12352200

属性

• 重组: expressed in E. coli
• 方案: ≥95% (SDS-PAGE)
• 表单: buffered aqueous solution
• 比活: >1000 units/mg protein
• 分子量: inactive proenzyme 56 kDa (active form consists of 17 kDa and 10 kDa subunits); ≥30 kDa
• UniProt登记号: P42575
• 储存温度: −20°C
• 基因信息: human ... CASP2(835)

说明

生化/生理作用

Caspase 2 plays a major role in both positive and negative regulation of programmed cell death. It exists as two spliced variants, Ich-1L (long) and Ich-1S (short). Functionally, the two forms differ in that overexpression of the long form will induce apoptosis, while overexpression of the short form suppresses cell death.

Caspase 2 plays a major role in both positive and negative regulation of programmed cell death; exists as two spliced variants, Ich-1L (long) and Ich-1S (short).

单位定义

One unit will hydrolyze one nmol of N-Acetyl-Val-Asp-Val-Ala-Asp-AFC per min at pH 7.5 at 25 °C.

外形

Solution in 25 mM HEPES, pH 7.5, 0.15 M NaCl, 5 mM dithiothreitol, 10% sucrose, with 0.5 mg bovine serum albumin

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable