生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
存货情况
not available in Japan
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5 μg/mL using human skeletal muscle, myocytes
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... CCR1(1230)
mouse ... Ccr1(12768)
rat ... Ccr1(57301)
免疫原
synthetic peptide corresponding to the third extracellular loop of human C-C chemokine receptor 1 (CCR-1), conjugated to KLH. The immunizing peptide has 80% homology with the rat gene and 85% homology with the mouse gene.
生化/生理作用
CCR1 is a seven transmembrane protein that binds to macrophage inflammatory protein 1 alpha (MIP-1 alpha), monocyte chemoattractant protein 3 (MCP-3) and myeloid progenitor inhibitory factor-1 (MPIF-1). It has important role in protecting the host from inflammatory responses, viruses and parasites.
外形
Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
J Hesselgesser et al.
The Journal of biological chemistry, 273(25), 15687-15692 (1998-06-23)
The CC chemokines macrophage inflammatory protein-1alpha (MIP-1alpha) and RANTES (regulated on activation normal T cell expressed) have been implicated in rheumatoid arthritis and multiple sclerosis. Since their effects are mediated through the CCR1 chemokine receptor, we set up a small
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