AV37665

Anti-GPC3 antibody produced in rabbit

IgG fraction of antiserum

• 别名: Anti-Glypican 3
• UNSPSC代码: 12352203

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: IgG fraction of antiserum
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: lyophilized powder
• 分子量: 64 kDa
• 种属反应性: guinea pig, horse, canine, rat, mouse, rabbit, bovine, human
• 浓度: 0.5 mg - 1 mg/mL
• 技术: western blot: suitable
• NCBI登记号: NP_004475
• UniProt登记号: P51654
• 储存温度: −20°C
• 基因信息: human ... GPC3(2719)

说明

一般描述

Glypican 3 (GPC3), whose gene is associated with Simpson-Golabi-Behmel syndrome, is a heparin sulfate proteoglycan that is anchored to cell-surfaces via glycosylphosphatidylinositol (GPI). Overexpression of glypican 3 occurs in hepatocellular carcinomas (HCC). The silencing of glypican 3 expression leads to apoptosis in HCC.

特异性

Anti-GPC3 polyclonal antibody reacts with canine, bovine, human, mouse, and rat glypican 3 proteins.

免疫原

The immunogen for anti-GPC3 antibody: synthetic peptide derected towards the middle region of human GPC3

应用

Anti-GPC3 polyclonal antibody is used to tag glypican 3 protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe in cancer diagnosis to detect the presence of glypican 3 in hepatocellular carcinomas (HCC).

序列

Synthetic peptide located within the following region: FSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVL

外形

Lyophilized from PBS buffer with 2% sucrose

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable