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Merck

A4469

Sigma-Aldrich

Monoclonal Anti-ACTR/AIB1 antibody produced in mouse

clone AX 15, ascites fluid

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

AX 15, monoclonal

分子量

antigen 150 kDa

包含

0.035% sodium azide
30% glycerol

物種活性

human

技術

immunoprecipitation (IP): 15 μL using 500 μg of a BG-1 ovarian cell RIPA lysate.
western blot (chemiluminescent): 1:500 using RIPA lysates of BG-1 ovarian cancer cells

同型

IgG

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NCOA3(8202)

一般說明

ACTR associates with estrogen receptors in breast and ovarian cancers and stimulates transcription. Hence, ACTR has been implicated in the carcinogenesis of breast and ovarian tumors. Mouse monoclonal Anti-ACTR/AIB1 antibody recognizes human ACTR (150kD) and another doublet (110kD) by immunoblotting.
ACTR, a nuclear receptor coactivator, is also referred to as amplified in breast cancer 1 (AIB1), thyroid hormone receptor activator molecule-1 (TRAM-1), receptor-associated coactivator 3 (RAC3 and SRC3).

免疫原

GST fusion protein containing amino acids 605-1294 of human ACTR.

應用

Mouse monoclonal can be used for immunoprecipitation (15μL using 500μg of a BG-1 ovarian cell RIPA lysate) and western blot (1:500, using RIPA lysates of BG-1 ovarian cancer cells) assays.

外觀

The product is supplied as mouse ascites fluid, containing 30% glycerol and 0.035% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids


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S L Anzick et al.
Science (New York, N.Y.), 277(5328), 965-968 (1997-08-15)
Members of the recently recognized SRC-1 family of transcriptional coactivators interact with steroid hormone receptors to enhance ligand-dependent transcription. AIB1, a member of the SRC-1 family, was cloned during a search on the long arm of chromosome 20 for genes

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