生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
AX 15, monoclonal
分子量
antigen 150 kDa
包含
0.035% sodium azide
30% glycerol
物種活性
human
技術
immunoprecipitation (IP): 15 μL using 500 μg of a BG-1 ovarian cell RIPA lysate.
western blot (chemiluminescent): 1:500 using RIPA lysates of BG-1 ovarian cancer cells
同型
IgG
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NCOA3(8202)
一般說明
ACTR associates with estrogen receptors in breast and ovarian cancers and stimulates transcription. Hence, ACTR has been implicated in the carcinogenesis of breast and ovarian tumors. Mouse monoclonal Anti-ACTR/AIB1 antibody recognizes human ACTR (150kD) and another doublet (110kD) by immunoblotting.
ACTR, a nuclear receptor coactivator, is also referred to as amplified in breast cancer 1 (AIB1), thyroid hormone receptor activator molecule-1 (TRAM-1), receptor-associated coactivator 3 (RAC3 and SRC3).
免疫原
GST fusion protein containing amino acids 605-1294 of human ACTR.
應用
Mouse monoclonal can be used for immunoprecipitation (15μL using 500μg of a BG-1 ovarian cell RIPA lysate) and western blot (1:500, using RIPA lysates of BG-1 ovarian cancer cells) assays.
外觀
The product is supplied as mouse ascites fluid, containing 30% glycerol and 0.035% sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
Science (New York, N.Y.), 277(5328), 965-968 (1997-08-15)
Members of the recently recognized SRC-1 family of transcriptional coactivators interact with steroid hormone receptors to enhance ligand-dependent transcription. AIB1, a member of the SRC-1 family, was cloned during a search on the long arm of chromosome 20 for genes
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