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About This Item
经验公式（希尔记法）:
C6H15N5O · 2HCl
CAS号:
分子量:
246.14
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26
推荐产品
product name
L-Argininamide dihydrochloride,
化驗
≥98%
品質等級
形狀
powder
技術
ligand binding assay: suitable
顏色
white to off-white
儲存溫度
−20°C
SMILES 字串
Cl.N[C@@H](CCCNC(N)=N)C(N)=O
InChI
1S/C6H15N5O.ClH/c7-4(5(8)12)2-1-3-11-6(9)10;/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11);1H/t4-;/m0./s1
InChI 密鑰
BPQLYFCEVVKLLX-WCCKRBBISA-N
相关类别
應用
L-Argininamide dihydrochloride has been used as an additive to compare its effect over L-arg in egg lysozyme refolding studies. It has also been used as a component of substrate stock solution for enzymatic kyotorphin synthesis.
生化／生理作用
L-Argininamide (L-Arm) is a hydrophilic amino acid derivative that is used as a model compound in physicochemical characteristic studies of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - STOT SE 1
標靶器官
Eyes
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes.
Zece Zhu et al.
Chemical communications (Cambridge, England), 47(11), 3192-3194 (2011-01-29)
The nucleic acid minor groove binding dyes, DAPI and Hoechst 33258, were for the first time used in label-free aptamer-based sensors for L-argininamide. The synergy binding effect results in the enhancement of fluorescence of dyes. The method for detection of
Tao Li et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(23), 6718-6723 (2007-05-17)
We report a novel label-free method for the investigation of the adaptive recognition of small molecules by nucleic acid aptamers using capillary electrophoresis analysis. Cocaine and argininamide were chosen as model molecules, and the two corresponding DNA aptamers were used.
Max Keller et al.
Bioorganic & medicinal chemistry, 19(9), 2859-2878 (2011-04-16)
Fluorescently labelled NPY Y(1) receptor (Y(1)R) ligands were synthesized by connecting pyrylium and cyanine dyes with the argininamide-type Y(1)R antagonist core structure by linkers, covering a wide variety in length and chemical nature, attached to the guanidine group. The most
G Reid Bishop et al.
Biophysical chemistry, 126(1-3), 165-175 (2006-08-18)
The thermal stability and ligand binding properties of the L-argininamide-binding DNA aptamer (5'-GATCGAAACGTAGCGCCTTCGATC-3') were studied by spectroscopic and calorimetric methods. Differential calorimetric studies showed that the uncomplexed aptamer melted in a two-state reaction with a melting temperature T(m)=50.2+/-0.2 degrees C
Zhiai Xu et al.
Biosensors & bioelectronics, 26(12), 4733-4738 (2011-07-02)
Aptamers are nucleic acids that can selectively bind to a variety of targets. Aptamers usually undergo conformational transitions from a flexible or disordered structure into a rigid or ordered structure upon target-binding. This study describes a detection method for l-argininamide
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