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化驗
≥98% (HPLC)
形狀
solid
溶解度
DMSO: soluble 22 mg/mL
H2O: insoluble
SMILES 字串
Nc1ccccc1S(=O)(=O)Nc2cccc3cccnc23
InChI
1S/C15H13N3O2S/c16-12-7-1-2-9-14(12)21(19,20)18-13-8-3-5-11-6-4-10-17-15(11)13/h1-10,18H,16H2
InChI 密鑰
NIOOKXAMJQVDGB-UHFFFAOYSA-N
生化／生理作用
Inhibitor of cell cycle at G2 phase; apoptosis inducer.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Cíntia Tiemi Misugi Kayukawa et al.
Food chemistry, 303, 125388-125388 (2019-08-28)
Saponins are known for their bioactive and surfactant properties, showing applicability to the food, cosmetic and pharmaceutical industries. This work evaluated the saponins effects on Kluyveromyces lactis β-galactosidase activity and correlated these changes to the protein structure. Enzyme kinetic was
Carlos D Cruz-Hernández et al.
Cancer cell international, 20, 312-312 (2020-07-23)
Prostate cancer (PCa) is the second cause of cancer related death in North American men. Androgens play an important role in its progression by regulating the expression of several genes including fusion ones that results from structural chromosome rearrangements. TMPRSS2-ERG is a
Yun-Hee Kim et al.
Biochemical pharmacology, 69(9), 1333-1341 (2005-04-14)
We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS) as a potent cytotoxic compound that induces cell cycle arrest and apoptosis. Treatment of Jurkat T cells with
Mónica Y Herrera-Sotero et al.
Nutrition and cancer, 72(5), 768-777 (2019-08-27)
Background: Breast and prostate cancer are frequently diagnosed neoplasias in women and men around the world. The signaling of the androgen receptor (AR) influences the development of both tumors. Since therapies focused to block the receptor's activity have not been
Fredy Omar Beltrán-Anaya et al.
Molecular oncology, 13(4), 909-927 (2019-01-17)
Triple negative breast cancer (TNBC) represents an aggressive phenotype with poor prognosis compared with ER, PR, and HER2-positive tumors. TNBC is a heterogeneous disease, and gene expression analysis has identified seven molecular subtypes. Accumulating evidence demonstrates that long non-coding RNA
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