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Merck

A3013

Sigma-Aldrich

腺苷 2′(3′)-单磷酸混合异构体

别名:

酵母腺苷酸

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About This Item

经验公式(希尔记法):
C10H14N5O7P
CAS号:
分子量:
347.22
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

生物源

synthetic

化驗

≥45% (Adenosine-3′-monophosphate, HPLC)
≥97% (Total Adenosine-3′-monophosphate; Adenosine-2′-monophosphate, HPLC)
10-55% ( Adenosine-2′-monophosphate, HPLC)

形狀

powder

溶解度

1 M NH4OH: 50 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]3O.Nc4ncnc5n(cnc45)[C@@H]6O[C@H](CO)[C@@H](O)[C@H]6OP(O)(O)=O

InChI

1S/2C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20;11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2*2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t2*4-,6-,7-,10-/m11/s1

InChI 密鑰

UQRXDDDXDPEXNS-VQFZJOCSSA-N

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相关类别

一般說明

3′-单磷酸腺苷(3′-AMP)和2′-单磷酸腺苷(2′-AMP)是由金属依赖性磷酸二酯酶家族水解2′,3′-cAMP产生的代谢产物。2′-AMP和3′-AMP通过A2B受体抑制肾小球前血管平滑肌细胞和肾小球系膜细胞的增殖。

應用

腺苷2′(3′)-单磷酸盐混合异构体被用作分离和分离的标准物定量嘌呤(腺嘌呤和鸟嘌呤)和腺嘌呤核糖核苷单磷酸盐(2’-AMP 和 3’-AMP)通过等温高性能液体色谱法 (HPLC)。它也被用来筛选多个糖结合 ATPase A (MsbA) 转运蛋白。

聯結

不要与腺苷 2′:3′-环一磷酸混淆

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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The enzymatic cell-free metabolism of the novel hypoxia-selective cytotoxin 4-[3-(2-nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1) was investigated under hypoxic or aerobic conditions in the presence of purified reductive enzymes or isolated rat liver microsomes by monitoring the parent compound with HPLC-UV analysis. Enzymatic
G S Padiyar et al.
Journal of biomolecular structure & dynamics, 15(4), 803-821 (1998-03-26)
Crystal structures of lithium, sodium, potassium, calcium and magnesium salts of adenosine 2'-monophosphate (2'-AMP) have been obtained at atomic resolution by X-ray crystallographic methods. 2'-AMP.Li belongs to the monoclinic space group P2(1) with a = 7.472(3)A, b = 26.853(6) A
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Phosphorescence and ODMR measurements have been made on ribonuclease T1 (RNase T1), the mutated enzyme RNase T1 (Y45W), and their complexes with 2'GMP and 2'AMP. It is not possible to observe the phosphorescence of Trp45 in RNase T1 (Y45W). Only
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This paper is aimed to study the metabolic kinetics of nicousamide in rat liver microsomes and cytosol and to identify the major metabolite and drug metabolizing enzymes involved in the metabolism of nicousamide in rat and human liver microsomes by

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