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Merck
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文件

C2105

Sigma-Aldrich

Z-Val-Ala-Asp氟甲基酮

powder, ≥90% (TLC)

别名:

Z-VAD-FMK，未甲基化

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About This Item

经验公式（希尔记法）:
C21H28FN3O7
CAS号:
161401-82-7
分子量:
453.46
MDL號碼:
MFCD03452883
分類程式碼代碼:
12352209
PubChem物質ID:
329774926
NACRES:
NA.77

品質等級

200

化驗

≥90% (TLC)

形狀

powder

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

InChI 密鑰

SUUHZYLYARUNIA-YEWWUXTCSA-N

Amino Acid Sequence

Z-Val-Ala-Asp-OMe-FMK

生化／生理作用

非甲基化竞争性和不可逆抑制剂 caspase-1 以及其他 caspase可直接与纯化的酶一起使用。它不需要酯酶即可水解 O-甲酯，就像细胞可渗透的形式 Z-Val-Ala-Asp（OMe）氟甲基酮（货号 V-116）一样。

特點和優勢

该化合物在受体分类和信号转导手册的 半胱天冬酶 页面上有详细描述。如需浏览其他手册页面，请点击此处。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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