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化驗
≥95% (TLC)
形狀
powder
光學活性
[α]/D 9.0±1.0°, 3 hr, c = 0.1 in H2O
顏色
white
儲存溫度
−20°C
InChI
1S/C6H11O9P/c7-3(1-4(8)6(10)11)5(9)2-15-16(12,13)14/h3,5,7,9H,1-2H2,(H,10,11)(H2,12,13,14)/t3-,5+/m0/s1
InChI 密鑰
OVPRPPOVAXRCED-WVZVXSGGSA-N
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生化／生理作用
2-脱氢-3-脱氧-磷酸葡萄糖酸是2-脱氢-3-脱氧-磷酸葡萄糖酸醛缩酶的底物，该酶将其转化为D-甘油醛3-磷酸加丙酮酸盐。
磷酸戊糖途径，生成NADPH和戊糖；以及戊糖和葡萄糖醛酸酯的相互转化中的代谢产物；某些细菌的Entner-Doudoroff途径中的关键中间体，2-酮-3-脱氧-6-磷酸葡萄糖酸(KDPG)醛缩酶的底物，催化KDPG可逆裂解为丙酮酸和3-磷酸甘油醛。发现它是恶臭假单胞菌KT2440中苯乙酸代谢的碳分解代谢物抑制信号。Pu的表达主要通过PtsN抑制，以响应高水平的2-脱氢-3-脱氧葡萄糖酸-6-磷酸。
包裝
无底玻璃瓶。内含物装在插入的熔锥内。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Juhyun Kim et al.
Microbiology (Reading, England), 155(Pt 7), 2420-2428 (2009-05-02)
The growth pattern of Pseudomonas putida KT2440 in the presence of glucose and phenylacetic acid (PAA), where the sugar is used in preference to the aromatic compound, suggests that there is carbon catabolite repression (CCR) of PAA metabolism by glucose
Stephen W B Fullerton et al.
Bioorganic & medicinal chemistry, 14(9), 3002-3010 (2006-01-13)
In vivo, 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase catalyzes the reversible, stereospecific retro-aldol cleavage of KDPG to pyruvate and D-glyceraldehyde-3-phosphate. The enzyme is a lysine-dependent (Class I) aldolase that functions through the intermediacy of a Schiff base. Here, we propose a mechanism for
Viatcheslav Zaitsev et al.
Biochemistry, 57(26), 3797-3806 (2018-05-31)
The thermoacidophilic archaea Picrophilus torridus and Sulfolobus solfataricus catabolize glucose via a nonphosphorylative Entner-Doudoroff pathway and a branched Entner-Doudoroff pathway, respectively. Key enzymes for these Entner-Doudoroff pathways are the aldolases, 2-keto-3-deoxygluconate aldolase (KDG-aldolase) and 2-keto-3-deoxy-6-phosphogluconate aldolase [KD(P)G-aldolase]. KDG-aldolase from P.
Teresa del Castillo et al.
Journal of bacteriology, 189(18), 6602-6610 (2007-07-10)
Pseudomonas putida KT2440(pWW0) can use toluene via the TOL plasmid-encoded catabolic pathways and can use glucose via a series of three peripheral chromosome-encoded routes that convert glucose into 6-phosphogluconate (6PG), namely, the glucokinase pathway, in which glucose is transformed to
A new phosphorylated intermediate in glucose oxidation.
J MACGEE et al.
The Journal of biological chemistry, 210(2), 617-626 (1954-10-01)
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