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Merck

54008

Sigma-Aldrich

1,2-二油酰基-sn-丙三基-3-磷酸乙醇胺

≥98.0% (TLC)

别名:

3-sn-磷脂酰乙醇胺, 1,2-二油酰, L-β,γ-二油酰-α-脑磷脂, DOPE, PE(18:1(9Z)/18:1(9Z)), 二油酰磷脂酰乙醇胺

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About This Item

经验公式(希尔记法):
C41H78NO8P
CAS号:
分子量:
744.03
Beilstein:
1718431
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:

方案

≥98.0% (TLC)

表单

solid

官能团

ester

脂质类型

phosphoglycerides

储存温度

−20°C

SMILES字符串

CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-

InChI key

MWRBNPKJOOWZPW-CLFAGFIQSA-N

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应用

1,2-二油酰-sn-甘油-3-磷酸乙醇胺(DOPE)可与N-[1-(2,3-二油酰氧基)丙基] -N,N,N-三甲基甲基硫酸铵(DOTAP)形成异质脂质体而作为治疗剂的运载工具

包装

无底玻璃瓶。内含物装在插入的融合锥内。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Antonio A M Gasperini et al.
Langmuir : the ACS journal of surfaces and colloids, 31(11), 3308-3317 (2015-03-03)
This work presents a study of the association between low molecular weight hyaluronic acid (16 kDa HA) and cationic liposomes composed of egg phosphatidylcholine (EPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), and 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP). The cationic liposome/HA complexes were evaluated to determine their mesoscopic
Jonathan Langdown et al.
Blood, 124(12), 1951-1956 (2014-07-23)
In this study, we describe a novel thrombomodulin (TM) mutation (c.1611C>A) that codes for a change from cysteine 537 to a premature stop codon (p.Cys537Stop). Three members of a family with a history of posttraumatic bleeding were identified to be
Ryo Furukawa et al.
Biomaterials, 57, 107-115 (2015-04-29)
Mitochondrial genome-targeting nucleic acids are promising therapeutic candidates for treating mitochondrial diseases. To date, a number of systems for delivering genetic information to the cytosol and the nucleus have been reported, and several successful gene therapies involving gene delivery targeted
S Peraramelli et al.
Journal of thrombosis and haemostasis : JTH, 12(11), 1826-1837 (2014-08-29)
TFPI is a Kunitz-type protease inhibitor that downregulates the extrinsic coagulation pathway by inhibiting factor Xa (FXa) and FVIIa. All three Kunitz domains (KD1, KD2, and KD3) and protein S are required for optimal inhibition of FXa and FVIIa. There
Muneeb Ahmed et al.
PloS one, 10(7), e0128910-e0128910 (2015-07-15)
Radiofrequency thermal ablation (RFA) of hepatic and renal tumors can be accompanied by non-desired tumorigenesis in residual, untreated tumor. Here, we studied the use of micelle-encapsulated siRNA to suppress IL-6-mediated local and systemic secondary effects of RFA. We compared standardized

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